Characterizing an HSF1-dependent transcriptional program in metastatic lung adenocarcinoma

Authors

Hoj, Jacob P.

Pendergast, Ann M.

Description

Summary from the GEO: "The purpose of this study was to identify gene targets differentially regulated by shRNA-mediated knockdown of the HSF1 transcription factor in the brain-metastatic lung adenocarcinoma cell line PC9-BrM3." Overall design from the GEO: "Samples were analyzed for differential gene expression in PC9-BrM3 cells transduced with shRNAs against NTC (non-target control) versus HSF1....

Subject

Adenocarcinoma of Lung

Brain Neoplasms

Heat Shock Transcription Factors

Lung Neoplasms

RNA, Small Interfering

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